Endocrine Abstracts

Introduction: The adrenal incidentaloma is an asymptomatic tumor measuring at least one cm, discovered incidentally during a medical imaging examination. The adrenal incidentaloma continues to grow with technological advances and improved radiological examinations. Any adrenal incidentaloma involves the search for a secretion or malignant character. The objective of our study is to study the clinical, biological and etiological aspects of adrenal incidentalomas.<p class="a...

Introduction: Primary hyperparathyroidism JawTumor Syndrome is a rare genetic disorder characterized by the synchronous or metachronous occurrence of primary hyperparathyroidism and an ossifying fibroma of the maxilla and/or mandible, associated with an increased risk of parathyroid carcinoma.Observation: We report the case of a 30-year-old young woman who consulted for a limp in walking,6 months after having been operated for a juvenile ossifying fibrom...

Introduction: Gestational diabetes mellitus (GDM) arises from elevated glycemia during pregnancy, posing risks to both mother and fetus. Managing GDM involves close monitoring and dietary control, with antenatal insulin therapy (AIT). The aim of this study was to evaluate the efficiency of diverse maternal characteristics and biological indicators identified during GDM diagnosis in anticipating the inadequacy of dietary measures and the requirement for AIT to achieve glucose t...

Introduction: Growth hormone deficiency (GHD) is a rare cause of growth retardation whose diagnosis remains relatively late. Its etiologies are multiple, and its treatment could improve the stature prognosis of the children. The objective of this study was to describe the clinical, biological, radiological, and therapeutic characteristics of GHD, and its outcomes after treatment.Methods: A cross-sectional study was conducted in the Endocrinology departme...

Introduction : Few studies have considered the natural history of pituitary anatomy in Sheehan syndrome (SS), as seen on magnetic resonance imaging (MRI) or CT scan. An imaging study of the sella turcica was carried out in patients with SS. The aim was to look for correlations between radiological findings and the degree of endocrine insufficiency on the one hand, and diagnosis delay on the other.Methods: This is a retrospective study carried out between...

Introduction: Sheehan’s syndrome (SS) results from severe post-partum hemorrhage leading to necrosis of the pituitary gland. Here we describe the clinical characteristics of patients with Sheehan syndrome.Methods: We conducted a 44-year cohort study (1977 to 2021) of patients with SS followed at the endocrinology department of Farhat Hached Hospital in Sousse, Tunisia. Medical history, physical examination findings and laboratory investigations were...

Introduction: Hamartomas are benign tumors that occur in many different parts of the body. Brain locations of hamartoma are rare but still reported in few cases such as the tuber cinereum (TC) location. Children with hypothalamic hamartomas develop precocious puberty generally associated with gelastic seizures. However, TC hamartomas do not necessarily induce clinical symptoms. Amenorrhea has never been reported as a revealing symptom of TC hamartomas. Here we describe an atyp...

Introduction: Pituitary adenomas stand as the most prevalent form of tumorous pathology impacting the pituitary gland in adults. Their discovery might arise from either hypersecretion in functional adenomas or the manifestation of compression symptoms on neighboring structures. Detection of a pituitary adenoma can occur incidentally during various imaging modalities, encompassing both structural and functional assessments. This study documents a case involving the incidental d...

Introduction: Pregnancy induces significant hormonal alterations, potentially affecting thyroid hormones. Our study aimed to assess the prevalence of thyroid dysfunction in pregnant women diagnosed with gestational diabetes Mellitus (GDM).Methods: A descriptive study was conducted, including 197 pregnant women diagnosed with GDM, under the care and monitoring at the Diabetology, Endocrinology department in Farhat Hached university Hospital, Sousse Tunisi...

Introduction: Chromosomal abnormality 47, XYY, despite being present in approximately 1 in 1000 newborn boys, remains less known phenotypically and more than 85% of men are never diagnosed. Males with 47, XYY syndrome are described to be phenotypically normal. They present often a developmental delay, behavioral difficulties and learning disabilities that may be associated with accelerated growth rate and taller stature in adulthood. Endocrine disorders, especially pubertal de...